An international audit, conducted by an independent research firm, demonstrated that after 3+ months of using The Gupta Program participants experienced a significant increase in overall health and functioning for 14 of 16 different conditions, and approached a significant increase for the two other conditions.

In a 3-month randomized controlled trial among people suffering from Long COVID, The Gupta Program significantly reduced fatigue and increased energy. Additionally, the reduction in fatigue and increase in energy were much larger compared to a control group who received a structurally-equivalent wellness program.

In an 8-week randomized controlled trial among Fibromyalgia patients, The Gupta Program significantly reduced symptoms and increased health. These improvements were also much greater among those using The Gupta Program compared to a control group who received a structurally-equivalent wellness program.

In a 3-month randomized controlled trial among people suffering from ME/CFS or Fibromyalgia, The Gupta Program significantly increased physical health and energy, and reduced pain, symptom distress, and fatigue. These improvements far exceeded those experienced by patients who received standard care for ME/CFS or Fibromyalgia.

In a clinical audit of patients with ME/CFS, virtually all participants reported improvement, with two-thirds making considerable recoveries that reached 80%-100% full functioning.

After several years of suffering from ME/CFS and researching the illness, Ashok Gupta was able to facilitate his own recovery by developing what is now known as The Gupta Program. Though the program has been continually refined and improved over the last two decades, the hypothesis underlying it has remained largely the same. Most people who use The Gupta Program find the hypothesis very helpful in understanding what is happening in their body and how the program can provide a journey to recovery.